{"id":1293,"date":"2023-04-11T11:49:14","date_gmt":"2023-04-11T02:49:14","guid":{"rendered":"https:\/\/recl-ginza.com\/reclg-cn\/?page_id=1293"},"modified":"2023-05-23T11:30:51","modified_gmt":"2023-05-23T02:30:51","slug":"%e3%82%b9%e3%83%bc%e3%83%91%e3%83%bc%e6%8a%97%e9%85%b8%e5%8c%96%e6%b2%bb%e7%99%82","status":"publish","type":"page","link":"https:\/\/recl-ginza.com\/reclg-cn\/%e3%82%b9%e3%83%bc%e3%83%91%e3%83%bc%e6%8a%97%e9%85%b8%e5%8c%96%e6%b2%bb%e7%99%82\/","title":{"rendered":"\u8d85\u6297\u9178\u5316\u6cbb\u7597"},"content":{"rendered":"

Re clinic\u94f6\u5ea7\u7684\u6297\u6c27\u5316\u7597\u6cd5\u662f\u7ed3\u5408\u4e86exosome\u6cbb\u7597\u3001\u8840\u6db2\u81ed\u6c27\u6cbb\u7597\u548c\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u6cbb\u7597\u7684\u4e00\u79cd\u91cf\u8eab\u5b9a\u5236\u7684\u6297\u6c27\u5316\u7597\u6cd5\u3002<\/p>\n

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\u4eba\u4f53\u7ec6\u80de\u91cc\u4e5f\u6709\u540c\u6837\u7684\u9632\u6b62\u6c27\u5316\u4f5c\u7528\u7684\u5b58\u5728\u3002<\/p>\n

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\u6d3b\u6027\u6c27\u6b63\u786e\u6765\u8bf4\u662f\u53eb\u505a\u6d3b\u6027\u6c27\u79cd\uff08ROS\uff1areactive oxygen species\uff09\u3001\u662f\u53cd\u5e94\u6027\u8f83\u9ad8\u7684\u6d3b\u6027\u6c27\u79cd\u7684\u603b\u79f0\u3001\u8d85\u6c27\u5316\u7269\u3001\u8fc7\u6c27\u5316\u6c22\u3001\u7f9f\u57fa\u81ea\u7531\u57fa\u3001\u5355\u7ebf\u6001\u6c27\u7b49\u5728\u4f53\u5185\u8d77\u6c27\u5316\u5242\u7684\u4f5c\u7528\u3002 \u5176\u4e2d\u3001\u8d85\u6c27\u548c\u7f9f\u57fa\u81ea\u7531\u57fa\u5bf9\u8eab\u4f53\u6709\u7279\u522b\u8d1f\u9762\u7684\u5f71\u54cd\u3001\u4e5f\u88ab\u79f0\u4e3a\u81ea\u7531\u57fa\u3002<\/p>\n

\u8d85\u6c27\u5316\u7269\u88ab\u4e00\u4e2a\u7535\u5b50\u8fd8\u539f\u7684\u8fc7\u6c27\u5316\u6c22\u4e0d\u662f\u81ea\u7531\u57fa\uff0c\u800c\u662f\u6d3b\u6027\u6c27\u4e4b\u4e00\u3002 \u5f53SOD\u964d\u89e3\u8d85\u6c27\u5316\u7269\u65f6\u4f1a\u53d1\u751f\u8fd9\u79cd\u60c5\u51b5\u3002 \u7531\u4e8e\u8fc7\u6c27\u5316\u6c22\u53ef\u4ee5\u7a7f\u8fc7\u7ebf\u7c92\u4f53\u7684\u5185\u819c\u548c\u5916\u819c\u7b49\u7ec6\u80de\u819c\u3001\u56e0\u6b64\u5f53\u5b83\u4e0e\u7ec6\u80de\u4e2d\u7684\u94c1\u7b49\u8fc7\u6e21\u91d1\u5c5e\u53cd\u5e94\u65f6\u3001\u5c31\u4f1a\u88ab\u4e00\u4e2a\u7535\u5b50\u8fd8\u539f\u5e76\u4ea7\u751f\u7f9f\u57fa\u81ea\u7531\u57fa\u3002
\n\u7f9f\u57fa\u81ea\u7531\u57fa\u5728\u6d3b\u6027\u6c27\u79cd\u4e4b\u4e2d\u5177\u6709\u9ad8\u5ea6\u53cd\u5e94\u6027\u3001\u5e76\u4e14\u4f1a\u6c27\u5316\u86cb\u767d\u8d28\u3001\u8102\u8d28\u3001\u78b3\u6c34\u5316\u5408\u7269\u548c\u6838\u9178\u7b49\u751f\u7269\u6210\u5206\u3002 \u56e0\u6b64\u3001\u6d88\u9664\u4f5c\u4e3a\u7f9f\u57fa\u81ea\u7531\u57fa\u7684\u524d\u4f53\u7684\u8fc7\u6c27\u5316\u6c22\u5f88\u91cd\u8981\u3002 \u5728\u751f\u7269\u4f53\u4e2d\u3001\u6709\u4e00\u79cd\u6297\u6c27\u5316\u673a\u6784\u53ef\u4ee5\u8fd8\u539f\u8fc7\u6c27\u5316\u6c22\u3001\u4f8b\u5982\u8c37\u80f1\u7518\u80bd\u8fc7\u6c27\u5316\u7269\u9176\u3001\u5e76\u901a\u8fc7\u8fd9\u4e9b\u9176\u4fc3\u53cd\u5e94\u5c06\u5176\u8fd8\u539f\u4e3a\u6c34\u3002<\/p>\n

\u4f53\u5185\u4ea7\u751f\u6d3b\u6027\u6c27\u7684\u4e3b\u8981\u6765\u6e90\u662f\u7ebf\u7c92\u4f53\u3001\u7ebf\u7c92\u4f53\u4f1a\u6d88\u8017\u4f53\u5185\u7ea695%\u7684\u6c27\u6c14\u3001\u4f7f\u5176\u4e2d\u76841~3%\u8f6c\u5316\u4e3a\u6d3b\u6027\u6c27\u3002\u5f53\u6c27\u5206\u5b50\u88ab\u4e00\u4e2a\u7535\u5b50\u8fd8\u539f\u65f6\u3001\u5c31\u4f1a\u6210\u4e3a\u79f0\u4f5c\u8d85\u6c27\u5316\u7269\u7684\u6d3b\u6027\u6c27\u79cd\u3002
\n\u5728\u4f53\u5185\u3001\u5b58\u5728\u7740\u4e00\u79cd\u5c06\u8d85\u6c27\u5316\u7269\u5206\u89e3\u6210\u6c27\u6c14\u548c\u8fc7\u6c27\u5316\u6c22\u7684\u8d85\u6c27\u5316\u7269\u6b67\u5316\u9176\uff08SOD\uff1asuperoxide dismutase\uff09\u3001\u5728\u6d3b\u6027\u6c27\u4e2d\u5206\u89e3\u5bf9\u8eab\u4f53\u5f15\u8d77\u5f3a\u70c8\u7684\u8d1f\u9762\u5f71\u54cd\u7684\u8d85\u6c27\u5316\u7269\u3002\u4eba\u7c7bSOD\u6709\u4e09\u79cd\u7c7b\u578b\uff1aSOD1\u3001SOD2\u548cSOD3\u3002\u6211\u4eec\u7684\u7814\u7a76\u8868\u660e\u3001SOD3\u5bf9\u8eab\u4f53\u7684\u5f71\u54cd\u5c24\u4e3a\u91cd\u8981\u3001\u6211\u4eec\u7684\u9644\u5c5e\u516c\u53f8\u5df2\u4e3a\u5176\u7533\u8bf7\u4e86\u4e13\u5229\u3002\uff08<\/span>\u7279\u8bb86894652\uff09<\/span><\/p>\n

\u6982\u8981<\/p>\n

\u672c\u53d1\u660e\u6240\u8981\u89e3\u51b3\u7684\u95ee\u9898\u662f\u63d0\u4f9b\u4e00\u79cd\u80fd\u591f\u6291\u5236\u53c2\u4e0e\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u7684\u591a\u79cd\u7ec6\u80de\u56e0\u5b50\u3001\u5e76\u4fee\u590d\u53d7\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u635f\u4f24\u7684\u7ec4\u7ec7\u4fee\u590d\u5242\u3002
\n\uff1cSOD3\u4e0e\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u7684\u5173\u7cfb\uff1e
\n\u8001\u5e74\u4eba\u80ba\u90e8\u7684 SOD3 \u5c5e\u4e8e\u5f88\u5c11\u7684\u72b6\u6001\u3001\u8fd9\u8868\u660e\u4e0e\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u5bfc\u81f4\u7684 COVID-19 \u91cd\u75c7\u5316\u6709\u5173\u3002
\n\uff1c\u672c\u53d1\u660e\u7684\u65b0\u53d1\u73b0\uff1e
\n\u672c\u53d1\u660e\u53d1\u73b0\u3001\u6765\u6e90\u4e8e\u7279\u5b9a\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u57f9\u517b\u4e0a\u6e05\u6db2\u7684exosome\u7b49\u7ec6\u9897\u7c92\u542b\u6709\u5927\u91cf\u7684\u7ec6\u80de\u5916\u8d85\u6c27\u5316\u7269\u6b67\u5316\u9176\uff08SOD3\uff09\u5e76\u663e\u793a\u51fa\u8f83\u9ad8\u7684SOD\u6d3b\u6027\u3002
\n\u7136\u540e\u53d1\u73b0\u3001\u8fd9\u4e9b\u7ec6\u9897\u7c92\u672c\u8eab\u4e0d\u4ec5\u76f4\u63a5\u6291\u5236LPS\u7ed9\u836f\u8bf1\u5bfc\u7684\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u4e2d\u7684\u708e\u6027\u7ec6\u80de\u56e0\u5b50\u3001\u800c\u4e14\u8fd9\u4e9b\u7ec6\u9897\u7c92\u4e2d\u6240\u542b\u7684SOD3\u5177\u6709\u534f\u540c\u4f5c\u7528\u3001\u56e0\u4e3a\u5b83\u4eec\u5728\u7ec6\u80de\u56e0\u5b50\u4e2d\u7684IFN\u03b3\u548cTNF\u03b1\u7684\u5b58\u5728\u4e0b\u4fc3\u8fdb\u53d7\u635f\u7ec4\u7ec7\u7684\u4fee\u590d\u3002\u5230\u76ee\u524d\u4e3a\u6b62\u3001exosome\u4e2dSOD3\u5b58\u5728\u86cb\u767d\u8d28\u662f\u5df2\u77e5\u7684\u3002 \u7136\u800c\u3001\u6765\u6e90\u4e8e\u7279\u5b9a\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u57f9\u517b\u4e0a\u6e05\u6db2\u7684exosome\u7684SOD3\u6d3b\u6027\u975e\u5e38\u9ad8\u3001\u5e76\u4e14\u672c\u53d1\u660e\u4eba\u9996\u6b21\u53d1\u73b0\u5b83\u542b\u6709\u8d85\u8fc7\u6709\u6548\u91cf\u7684\u53ef\u4ee5\u4fee\u590d\u88ab\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u7834\u574f\u7684\u7ec4\u7ec7\u3002\u5982\u679c\u6ca1\u6709\u8fd9\u4e9b\u53d1\u73b0\u3001\u5c31\u4e0d\u53ef\u80fd\u60f3\u8c61\u51fa\u4e00\u79cd\u7ec4\u7ec7\u4fee\u590d\u5242\u3001\u5b83\u53ef\u4ee5\u6291\u5236\u53c2\u4e0e\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u7684\u7ec6\u80de\u56e0\u5b50\u5e76\u4fee\u590d\u88ab\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u635f\u574f\u7684\u7ec4\u7ec7\u3002<\/span>
\n\u800c\u4e14<\/span>SOD3\u5f88\u4f4e\u7684\u8001\u5e74\u4eba\uff08\u975e\u7279\u8bb8\u6587\u732e\uff16\uff1b\uff21\uff2e\uff34\uff29\uff2f\uff38\uff29\uff24\uff21\uff2e\uff34\uff33\u3000\uff06\u3000\uff32\uff25\uff24\uff2f\uff38\u3000\uff33\uff29\uff27\uff2e\uff21\uff2c\uff29\uff2e\uff27\uff08\uff12\uff10\uff12\uff10\uff09\u3001\u3000\uff13\uff13\u3001\u3000\uff12\uff09\u3001\u7531\u4e8eSOD 3\u8f83\u4f4e\u3001\u56e0\u6b64\u9884\u8ba1\u4e0d\u80fd\u4ec5\u901a\u8fc7\u6291\u5236\u7ec6\u80de\u56e0\u5b50\u6765\u8fdb\u884c\u7ec4\u7ec7\u4fee\u590d\u3001\u4f46\u662f\u6839\u636e\u672c\u53d1\u660e\u3001\u8001\u5e74\u4eba\u4e2d\u53d7\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u635f\u4f24\u7684\u7ec4\u7ec7\u53ef\u4ee5\u663e\u7740\u4fee\u590d\u3002<\/p>\n

\u4f5c\u4e3a\u89e3\u51b3\u4e0a\u8ff0\u95ee\u9898\u7684\u6df1\u5165\u7814\u7a76\u7684\u7ed3\u679c\u3001\u672c\u53d1\u660e\u4eba\u53d1\u73b0\u6765\u81ea\u7279\u5b9a\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u57f9\u517b\u4e0a\u6e05\u6db2\u7684\u7ec6\u9897\u7c92\u5982exosome\u542b\u6709\u7ec6\u80de\u5916\u8d85\u6c27\u5316\u7269\u6b67\u5316\u9176\uff08SOD 3\uff09\u5e76\u8868\u73b0\u51fa\u9ad8SOD\u6d3b\u6027\u3002\u7136\u540e\u53d1\u73b0\u901a\u8fc7\u4f7f\u7528\u8fd9\u4e9b\u7ec6\u9897\u7c92\u3001\u53c2\u4e0e\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u7684\u591a\u4e2a\u7ec6\u80de\u56e0\u5b50\u53ef\u4ee5\u88ab\u663e\u8457\u6291\u5236\u3002<\/p>\n

<\/h1>\n

\u8fd1\u5e74\u6765\u3001\u6297\u6c27\u5316\u80fd\u529b\u7684\u5f3a\u5ea6\u4e00\u76f4\u53d7\u5230\u5173\u6ce8\u3002 \u5b83\u6709\u671b\u63d0\u4f9b\u5305\u62ec\u7f8e\u80a4\u6548\u679c\u5728\u5185\u7684\u9632\u8870\u8001\u62a4\u7406\u3001\u9884\u9632\u4e0e\u751f\u6d3b\u65b9\u5f0f\u6709\u5173\u7684\u75be\u75c5\u548c\u9632\u6b62\u8870\u8001\u3002<\/p>\n

Exosome\u6cbb\u7597<\/span><\/strong><\/h3>\n

\u7efc\u4e0a\u6240\u8ff0\u3001\u6765\u6e90\u4e8e\u843d\u53f6\u7259\u9ad3\u5e72\u7ec6\u80de\u7684SOD3\u5728SOD\u4e2d\u7279\u522b\u503c\u5f97\u6ce8\u76ee\u3002\u5728\u6211\u4eec\u7684\u8bca\u6240\u3001\u6211\u4eec\u4e3a\u4e86\u6709\u6548\u5730\u7ed3\u5408\u8fd9\u4e2aSOD3\u5efa\u8bae\u4f7f\u7528SGFexosome\u70b9\u6ef4\u3002<\/p>\n

1.\u9884\u9632\u52a8\u8109\u786c\u5316<\/h3>\n

\u636e\u8bf4SOD\u9176\u548cSOD\u6837\u6210\u5206\u5bf9\u52a8\u8109\u786c\u5316\u4e5f\u80fd\u663e\u793a\u51fa\u6548\u679c\u3002\u636e\u8bf4\u52a8\u8109\u786c\u5316\u662f\u8840\u7ba1\u7684\u8001\u5316\u73b0\u8c61\u3001\u662f40\u5c81\u4ee5\u4e0a\u4eba\u7fa4\u4e2d\u5e38\u89c1\u7684\u75c7\u72b6\u3001\u5f53\u8840\u6d41\u56e0\u52a8\u8109\u786c\u5316\u800c\u6076\u5316\u65f6\u3001\u5927\u8111\u548c\u5fc3\u810f\u7b49\u5404\u79cd\u5668\u5b98\u7684\u529f\u80fd\u4f1a\u53d7\u5230\u4f24\u5bb3\u3002SOD\u9176\u548cSOD\u6837\u6210\u5206\u5177\u6709\u53bb\u9664\u6d3b\u6027\u6c27\u7684\u80fd\u529b\u3001\u6d3b\u6027\u6c27\u662f\u52a8\u8109\u786c\u5316\u7684\u539f\u56e0\u4e4b\u4e00\u3001\u56e0\u6b64\u5b83\u4eec\u88ab\u8ba4\u4e3a\u5bf9\u9884\u9632\u52a8\u8109\u786c\u5316\u662f\u6709\u6548\u7684\u3002<\/p>\n

2.\u6539\u5584\u9ad8\u8840\u538b<\/h3>\n

SOD\u9176\u88ab\u671f\u5f85\u7740\u6709\u6548\u9884\u9632\u548c\u6539\u5584\u7cd6\u5c3f\u75c5\u3002\u6295\u4e0eSOD\u6837\u6210\u5206\u4e4b\u540e\u7684\u7ed3\u679c\u3001\u8bc1\u5b9e\u4e86\u6709\u6291\u5236\u8840\u7cd6\u503c\u5347\u9ad8\u7684\u6548\u679c\u3002 \u56e0\u6b64\u3001SOD\u9176\u5df2\u88ab\u8bc1\u660e\u5728\u9884\u9632\u548c\u6cbb\u7597\u7cd6\u5c3f\u75c5\u65b9\u9762\u662f\u6709\u6548\u7684\u3002<\/p>\n

3.\u7ec6\u80de\u7684\u5065\u5eb7\u7ef4\u62a4\u6548\u679c<\/h3>\n

SOD\u9176\u88ab\u671f\u5f85\u7740\u6709\u6548\u9884\u9632\u548c\u6539\u5584\u7cd6\u5c3f\u75c5\u3002\u6295\u4e0eSOD\u6837\u6210\u5206\u4e4b\u540e\u7684\u7ed3\u679c\u3001\u8bc1\u5b9e\u4e86\u6709\u6291\u5236\u8840\u7cd6\u503c\u5347\u9ad8\u7684\u6548\u679c\u3002 \u56e0\u6b64\u3001SOD\u9176\u5df2\u88ab\u8bc1\u660e\u5728\u9884\u9632\u548c\u6cbb\u7597\u7cd6\u5c3f\u75c5\u65b9\u9762\u662f\u6709\u6548\u7684\u3002\u7531\u4e8e\u538b\u529b\u548c\u5438\u70df\u5bfc\u81f4\u6d3b\u6027\u9176\u7684\u589e\u52a0\u3001\u5b83\u53ef\u80fd\u4f1a\u653b\u51fb\u4f53\u5185\u7684\u7ec6\u80de\u3001\u751a\u81f3\u7834\u574f\u7ec6\u80de\u4e2d\u7684\u57fa\u56e0\u3002 \u5982\u679c\u57fa\u56e0\u88ab\u7834\u574f\u3001\u6b63\u5e38\u7684\u529f\u80fd\u548c\u518d\u751f\u5c06\u662f\u4e0d\u53ef\u80fd\u7684\u3002\u7ed3\u679c\u3001\u5b83\u4f1a\u5bfc\u81f4\u8870\u8001\u4ee5\u53ca\u5f15\u8d77\u5404\u79cd\u75be\u75c5\u3002 \u7531\u4e8eSOD\u9176\u5177\u6709\u4ece\u7ec6\u80de\u548cDNA\u4e2d\u300c\u53bb\u9664\u6d3b\u6027\u9176\u7684\u529f\u80fd\u300d\u3001\u56e0\u6b64\u53ef\u4ee5\u671f\u5f85\u5b83\u4eec\u5177\u6709\u9884\u9632\u548c\u6539\u5584\u8870\u8001\u4ee5\u53ca\u9884\u9632\u548c\u6539\u5584\u75be\u75c5\u7b49\u6548\u679c\u3002<\/p>\n

4.\u7f8e\u80a4\u6548\u679c<\/h3>\n

\u8fc7\u91cf\u7684\u6d3b\u6027\u9176\u4f1a\u635f\u5bb3\u7ec6\u80de\u3001\u56e0\u6b64\u76ae\u80a4\u7ec6\u80de\u65e0\u6cd5\u6b63\u5e38\u518d\u751f\u3002 \u7ed3\u679c\u3001\u5b83\u4f1a\u5ef6\u8fdf\u80a4\u8272\u53d8\u767d\u3001\u5bfc\u81f4\u53d8\u6210\u8870\u8001\u3001\u677e\u5f1b\u3001\u6c34\u5206\u4e0d\u8db3\u548c\u7c97\u7cd9\u7684\u76ae\u80a4\u3002
\n\u4e0eNMN\u7ef4\u751f\u7d20C\u548c\u81ed\u6c27\u7597\u6cd5\u4e00\u6837\u3001\u7531\u4e8eSOD\u9176\u7684\u4f5c\u7528\u3001\u300c\u7ec6\u80de\u7684\u518d\u751f\u300d\u6709\u671b\u5ef6\u7f13\u8870\u8001\u800c\u5bfc\u81f4\u7684\u8eab\u4f53\u529f\u80fd\u4e0b\u964d\u3001\u5e76\u4fdd\u6301\u6bd4\u5b9e\u9645\u5e74\u9f84\u66f4\u5e74\u8f7b\u3001\u66f4\u5065\u5eb7\u7684\u8eab\u4f53\u529f\u80fd\u3002<\/p>\n

\u4e0eSOD\u76f8\u540c\u7684\u6cbb\u7597\u65b9\u6cd5<\/h1>\n

\u3010exosome\u6cbb\u7597\u3001\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u3001NMN \u70b9\u6ef4\u3001\u81ed\u6c27\u7597\u6cd5\u3011\u8fd9\u4e9b\u6cbb\u7597\u65b9\u6cd5\u7684\u5171\u540c\u70b9\u662f\u3001\u7531\u4e8e\u7ec6\u80de\u8001\u5316\u548c\u7f3a\u4e4f\u7ef4\u751f\u7d20\u548cNMN\u75c7\u72b6\u7684\u6539\u5584\u3002\u867d\u7136\u5bf9\u5065\u5eb7\u7ef4\u6301\u6709\u5f71\u54cd\u3001\u4f46\u9884\u8ba1\u5b83\u5177\u6709\u5ef6\u7f13\u56e0\u8870\u8001\u5f15\u8d77\u7684\u8eab\u4f53\u529f\u80fd\u4e0b\u964d\u7684\u6548\u679c\u3001\u5e76\u901a\u8fc7\u5c06NMN\u5438\u6536\u5230\u4f53\u5185\u6765\u4fdd\u6301\u6bd4\u5b9e\u9645\u5e74\u9f84\u5e74\u8f7b\u7684\u5065\u5eb7\u8eab\u4f53\u529f\u80fd\u3002\u300c\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u8f93\u6db2\u300d\u53ef\u4ee5\u89e3\u6bd2\u6d3b\u6027\u6c27\u3001\u7531\u4e8e\u6297\u6c27\u5316\u4f5c\u7528\u6d3b\u6027\u6c27\u88ab\u8ba4\u4e3a\u662f\u8870\u8001\u7684\u539f\u56e0\u3002\u5e76\u4e14\u5bf9\u4e8e\u8870\u8001\u62a4\u7406\u548c\u7f8e\u767d\u7b49\u7f8e\u5bb9\u6548\u679c\u4ee5\u53ca\u75be\u75c5\u9884\u9632\u548c\u529f\u80fd\u6539\u5584\u975e\u5e38\u6709\u6548\u3002NMN\u548c\u7ef4\u751f\u7d20C\u7684\u51cf\u5c11\u5bfc\u81f4\u7ec6\u80de\u8001\u5316\u548c\u514d\u75ab\u529b\u51cf\u5f31\u3001\u5bfc\u81f4\u5404\u79cd\u75be\u75c5\u3002\u8fdb\u884c\u8fd9\u4e9b\u9884\u9632\u548c\u6539\u5584\u7684\u6b63\u662f\u8fd9\u4e2a\u300c\u7ec6\u80de\u518d\u751f\u300d\u6cbb\u7597\u3002 \u53ef\u4ee5\u9884\u671f\u8fd9\u4e2a\u975e\u5e38\u6709\u6548\u3001\u56e0\u4e3a\u8fd9\u4e2a\u662f\u76f4\u63a5\u4ece\u8840\u6db2\u4e2d\u5438\u6536\u6210\u5206\u7684\u3002 \u5728\u6211\u4eec\u533b\u9662\u3001\u6211\u4eec\u7684\u76ee\u6807\u662f\u901a\u8fc7\u4ece\u6cbb\u6108\u7ec6\u80de\u6765\u9884\u9632\u548c\u6539\u5584\u5404\u79cd\u75c7\u72b6\u3002<\/p>\n

\u8840\u6db2\u81ed\u6c27\u7597\u6cd5<\/strong><\/span><\/h3>\n

\u8fd9\u662f\u4e00\u79cd\u901a\u8fc7\u5bf9\u8eab\u4f53\u65bd\u52a0\u9002\u5ea6\u6c27\u5316\u538b\u529b\u6765\u6fc0\u6d3b\u514d\u75ab\u529f\u80fd\u548c\u6297\u6c27\u5316\u529f\u80fd\u7684\u533b\u5b66\u6cbb\u7597\u65b9\u6cd5\u3002 \u81ed\u6c27\u4f1a\u5bf9\u7ec6\u80de\u65bd\u52a0\u9002\u5ea6\u7684\u6c27\u5316\u538b\u529b\u3002
\n\u5f53\u7ec6\u80de\u53d7\u5230\u9002\u5e94\u6027\u6c27\u5316\u538b\u529b\u65f6\u3001\u5b83\u4eec\u53ef\u4ee5\u5728\u4e4b\u540e\u5bf9\u66f4\u5f3a\u7684\u538b\u529b\u505a\u51fa\u53cd\u5e94\u3002 \u8fd9\u88ab\u79f0\u4e3a\u5174\u594b\u6548\u5e94\u3002 \u901a\u8fc7\u8840\u6db2\u53cd\u5e94\u4e0e\u77ed\u5bff\u547d\u7684\u6d3b\u6027\u6c27\u4ea7\u751f\u8fc7\u6c27\u5316\u6c22\u5e76\u9010\u6e10\u6c27\u5316\u3002 \u5bf9\u4e8e\u767d\u8840\u7403\u3001\u5b83\u901a\u8fc7NFkB\u6d3b\u5316\u4fc3\u8fdb\u7ec6\u80de\u56e0\u5b50\u7b49<\/span>\u708e\u75c7\u4ecb\u8d28\u7684\u53d1\u73b0\u3002\u5bf9\u4e8e\u7ea2\u8840\u7403\uff0c\u5b83\u80fd\u6539\u5584\u7f3a\u8840\u7ec4\u7ec7\u4e2d\u7684\u8840\u6d41\u91cf\uff0c\u4fc3\u8fdb O2 \u4f9b\u5e94\uff0c\u5e76\u4e14\u589e\u52a0\u7cd6\u9175\u89e3\u3001\u589e\u52a0 G6PDH \u6d3b\u6027\u3001\u589e\u52a0 ATP \u548c\u589e\u52a0 2.3DPG \u6765\u6539\u5584\u65b0\u9648\u4ee3\u8c22\u3002\u5bf9\u4e8e\u8840\u5c0f\u677f\u5982PDGF\u3001TGF-\u03b2\u548cEGF\u7b49\u6210\u957f\u56e0\u5b50\u88ab\u91ca\u653e\u4f5c\u7528\u4e8e\u6108\u5408\u4f24\u53e3\u3002 \u957f\u5bff\u547d\u7684\u60c5\u62a5\u4f20\u8fbe\u7269\u8d284HNE\u548c\u5176\u4ed6\u8102\u8d28\u6c27\u5316\u7269\u5728\u5168\u8eab\u5faa\u73af\u3001\u4ee5\u6fc0\u6d3b\u8c37\u80f1\u7518\u80bd\u5408\u6210\uff0c\u8bf1\u5bfc\u6297\u6c27\u5316\u9176\u3001\u5e76\u589e\u5f3aNO\u7684\u4ea7\u751f\u3002 \u8fd9\u4e9b\u5728\u5168\u8eab\u5faa\u73af\u3001\u88ab\u8ba4\u4e3a\u53ef\u4ee5\u4fc3\u8fdb\u6297\u708e\u4f5c\u7528\u3001\u589e\u5f3a\u6297\u6c27\u5316\u4f5c\u7528\u3001\u6fc0\u6d3b\u514d\u75ab\u7cfb\u7edf\u3001\u548c\u6539\u5584\u8840\u6db2\u5faa\u73af\u3002<\/p>\n

\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C<\/h3>\n

\u7ef4\u751f\u7d20C\u4fc3\u8fdb\u80f6\u539f\u86cb\u767d\uff08\u5f39\u6027\u86cb\u767d\uff09\u7684\u4ea7\u751f\u3001\u80f6\u539f\u86cb\u767d\u662f\u4e00\u79cd\u4fdd\u6301\u76ae\u80a4\u5f39\u6027\u3001\u9632\u6b62\u7455\u75b5\u548c\u76b1\u7eb9\u3001\u5e76\u4f7f\u76ae\u80a4\u7d27\u81f4\u548c\u65b0\u9c9c\u7684\u7ec6\u80de\u3002\u5e76\u589e\u5f3a\u514d\u75ab\u529b\u3002 \u901a\u8fc7\u6fc0\u6d3b\u767d\u7ec6\u80de\u4fc3\u8fdb\u5e72\u6270\u7d20\u7684\u4ea7\u751f\u3001\u589e\u5f3a\u8eab\u4f53\u7684\u514d\u75ab\u529f\u80fd\u3002\u5bf9\u4e8e\u80f6\u539f\u86cb\u767d\u7684\u4ea7\u751f\u81f3\u5173\u91cd\u8981\u3001\u80f6\u539f\u86cb\u767d\u662f\u9aa8\u9abc\u548c\u808c\u8171\u4e2d\u7684\u7ed3\u5408\u86cb\u767d\u3002 \u56e0\u6b64\u3001\u5982\u679c\u7f3a\u4e4f\u7ef4\u751f\u7d20C\u3001\u80f6\u539f\u86cb\u767d\u5c31\u4e0d\u4f1a\u5408\u6210\u3001\u8840\u7ba1\u5c31\u4f1a\u53d8\u8106\u3001\u5bb9\u6613\u51fa\u8840\u3002\u300c\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u8f93\u6db2\u300d\u53ef\u4ee5\u89e3\u6bd2\u6d3b\u6027\u6c27\u3001\u6d3b\u6027\u6c27\u56e0\u5176\u6297\u6c27\u5316\u4f5c\u7528\u800c\u88ab\u8ba4\u4e3a\u662f\u8870\u8001\u7684\u539f\u56e0\u3001\u5e76\u4e14\u5bf9\u4e8e\u8870\u8001\u62a4\u7406\u548c\u7f8e\u767d\u7b49\u7f8e\u5bb9\u6548\u679c\u4ee5\u53ca\u75be\u75c5\u9884\u9632\u548c\u529f\u80fd\u6539\u5584\u975e\u5e38\u6709\u6548\u3002\u6b64\u5916\u4ee5\u4f5c\u4e3a\u9884\u9632\u75be\u75c5\u548c\u6539\u5584\u529f\u80fd\u4e3a\u76ee\u7684\u4e5f\u975e\u5e38\u6709\u6548\u3002\u8fd1\u5e74\u6765\u3001\u5b83\u4f5c\u4e3a\u4e00\u79cd\u6709\u6548\u7684\u764c\u75c7\u6cbb\u7597\u65b9\u6cd5\u548c\u764c\u75c7\u9884\u9632\u3001\u51e0\u4e4e\u6ca1\u6709\u526f\u4f5c\u7528\u3001\u53ef\u4ee5\u63d0\u9ad8\u514d\u75ab\u529b\u3001\u56e0\u6b64\u5907\u53d7\u5173\u6ce8\u3002<\/p>\n

 <\/p>\n

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